Obstetrics (Malaria/HIV)

Management of HIV Infected Pregnant Patients in Malaria-Endemic Areas

Published in AIDS Weekly, November 1st, 1999

Problems may arise when antimalarial agents are combined with antiretroviral drugs in pregnant women.

"Chemotherapy in pregnancy is an intricate process requiring prudent use of pharmacologic agents. Malarial infection during pregnancy is often fatal, and prophylaxis against the causative parasite necessitates rational therapeutic intervention," stated researchers from the United States.

Among the prophylactic drugs used to combat malaria during pregnancy are chloroquine, mefloquine, proguanil, pyrimethamine, and pyrimethamine-sulfadoxine.

"Use of these agents has been based on a risk-benefit criterion, without appropriate...

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Source: AIDS Weekly (1999-11-01)

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