AIDS Therapies (Pediatrics)

Combination Therapy More Effective than Monotherapy in Children

Published in AIDS Weekly, November 15th, 1999

Combination therapy with zidovudine and didanosine worked better than monotherapy against central nervous system disease in HIV infected children.

C. Raskino and colleagues compared the impact of three different nucleoside reverse transcriptase inhibitor regimens - zidovudine (ZDV) monotherapy, didanosine (ddI) monotherapy, and ZDV plus ddI combination therapy - on central nervous system (CNS) outcomes in symptomatic human immunodeficiency virus (HIV) infected children.

They reported their findings in a recent issue of the journal Pediatrics ("Neurologic, Neurocognitive, and Brain Growth Outcomes in Human Immunodeficiency Virus-Infected Children...

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Source: AIDS Weekly (1999-11-15)

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