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Epidemiology

Predominance of Distinct HIV-1 Subtype in West Africa Discovered

Published in AIDS Weekly, November 22nd, 1999

There is an epidemic spread of a distinct subtype A/G recombinant of HIV-1 in Guinea-Bissau, West Africa, researchers from Sweden reported.

"Guinea-Bissau in West Africa has the highest prevalence of human immunodeficiency virus (HIV)-2 infection in the world, but recently the HIV-1 prevalence increased rapidly with the subsequent appearance of HIV-1 and HIV-2 dual infections," wrote S. Andersson and colleagues from the Department Immunology, Solna, Sweden.

"Information about the genetic subtypes of HIV in the region is limited, therefore, we characterized the envV3 region of HIV-1 and HIV-2 variants through direct DNA sequencing of peripheral...

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