Autoimmunity (Cell Signalling)

T Cells Balance between Dying, Autoreactivity

Published in AIDS Weekly, November 29th, 1999

A study at the University of Minnesota, USA, suggests that persons whose T cells have been depleted may see a rebound of T cells in response to the body's own proteins, although not as severe as in the case of autoimmune diseases.

The work was published in the Proceedings of the National Academy of Sciences.

T cells, the cells that carry out the body's search-and-destroy operations against foreign cells, must first learn to recognize the body's own cells. That is done early in life in the thymus gland, where young T cells are exposed to proteins that signal "self." Later, when the cells encounter foreign proteins not in the company of self...

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Source: AIDS Weekly (1999-11-29)

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