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Virology

Evolutionary Link is Suggested for HIV-1

Published in AIDS Weekly, December 13th, 1999

by Salynn Boyles, Senior Editor -- There appears to be an evolutionary link between HIV-1 and a group of endogenous retroviruses first seen some 30 million years ago.

Duke University, USA, researchers describe the identification of a regulatory protein encoded by a human endogenous retrovirus which has significant implications for the study of the evolution of retroviruses, including HIV-1.

Endogenous retroviruses are encoded within the genomes of all higher eukaryotes and arose from the infection of germ cells by exogenous retroviruses. These infections generally occurred in the distant past and most endogenous retroviruses have suffered...

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