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AIDS Therapies

Pokeweed Antiviral Protein Shows Promise

Published in AIDS Weekly, December 27th, 1999

Pokeweed antiviral protein (PAP), a natural product isolated from the pokeweed plant, shows great potential as a new anti-HIV drug, researchers from the Hughes Institute, St. Paul, Minnesota, report.

In a clinical study, nine out of nine patients were treated with a single dose of this agent and tolerated the treatment with no side effects. Most notably, six out of six patients evaluated for a response of their disease showed reduction of their viral burden. These patients also showed a 3-to-5 fold enhancement of their immune function represented by their natural killer cells and B-cells.

The results of this study are reported by Hughes Institute...

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