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AIDS Therapies

Early Viral Reduction May Not Affect Resting Energy Expenditure

Published in AIDS Weekly, January 31st, 2000

Protease inhibitor therapy improved body composition and metabolic parameters in patients with HIV infection, according to research from Austria.

H. Pernerstorferschoen and colleagues performed a study to investigate whether protease inhibitor (PI) (nelfinavir)-containing highly active antiretroviral therapy (HAART) affects body composition differently in HIV infected and AIDS patients without wasting syndrome ("Beneficial effects of protease inhibitors on body composition and energy expenditure: a comparison between HIV infected and AIDS patients," AIDS, December 3, 1999;13(17):2389-2396).

The researchers also set out to delineate the changes...

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