Published in AIDS Weekly, February 7th, 2000
Existing drugs stop the virus from reproducing itself inside an infected cell by deactivating 2 of the virus' enzymes called reverse transcriptase and protease. But some strains of HIV have evolved to be resistant to these drugs.
In the January 28, 2000, issue of Science, D. J. Hazuda and colleagues at Merck Research Laboratories, West Point, Pennsylvania, reported they have targeted a third enzyme, called integrase, that is critical for the virus' ability to slip its DNA into the host cell's...
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