AIDS Therapies

Impact of Ritonavir on Fat Distribution Studied

Published in AIDS Weekly, March 13th, 2000

Researchers at Seattle's University of Washington studied the effect of ritonavir on lipid and post-heparin lipase activities in persons not infected with HIV.

Intensive therapy aimed at HIV infection with highly active antiretroviral therapy (HAART) dramatically reduces viral loads and improves immune status. Abnormalities of lipid levels, body fat distribution, and insulin resistance have been commonly reported after starting HAART.

"Whether the lipid abnormalities result from changes in metabolism after an improvement in HIV status or are partly attributable to the effects of protease inhibitor use is unknown," Q. Zambon and colleagues wrote in...

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Source: AIDS Weekly (2000-03-13)

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