Viral Genomes
Genetic Footprinting Used for Studying HIV-1 Genome
Published in AIDS Weekly, March 20th, 2000
L.C. Laurent and colleagues presented a detailed and quantitative analysis of the functional characteristics of the 1,000-nucleotide segment at the 5' end of the human immunodeficiency virus type 1 (HIV-1) RNA genome.
"This segment of the viral genome contains several important cis-acting sequences, including the TAR, polyadenylation, viral att site, minus-strand primer-binding site, and 5' splice donor sequences, as well as coding sequences for the matrix protein and the N-terminal half of the capsid protein," Laurent et al. wrote ("Functional...
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Source: AIDS Weekly (2000-03-20)
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