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Long-Term Non-Progressors

Researchers Discover Why Some HIV Infected People Don't Develop AIDS

Published in AIDS Weekly, March 27th, 2000

For reasons largely unknown, a small number of HIV infected individuals remain symptom-free long after AIDS normally would have appeared. Scientists from the U.S. National Institute of Allergy and Infectious Diseases (NIAID) and their co-workers now report how a small subgroup of these so-called long-term nonprogressors (LTNPs) may avoid disease.

Their research, which appeared in the March 14, 2000, Proceedings of the National Academy of Sciences, provides new information that one day may be used in developing vaccines or other therapies to control HIV infection (S.A. Migueles et al., "HLA B*5701 is highly associated with restriction of virus replication in a...

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