Expression Vectors

HIV 1 and 2 Promoter Constructs Elicit More Interleukin 2

Published in AIDS Weekly, April 10th, 2000

A study of expression vectors has shown that HIV 1 and 2 promoter constructs can produce large quantities of interleukin 2 (IL-2) in human cancer cell lines.

Researchers at the University of Arizona College of Medicine conducted this study, which was reported in the International Journal of Molecular Medicine, ("Construction of new amplifier expression vectors for high levels of IL-2 gene expression," Int J Molecular Med, 2000;5(3):295-300).

"Currently, expression vectors based on the human cytomegalovirus (CMV) promoter give the highest levels of expression. We have attempted to construct new IL-2 expression vectors to test whether...

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Source: AIDS Weekly (2000-04-10)

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