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HIV Immunotherapy

Clinical Trial Will Test Controlled 'Drug Holidays' to Counter HIV

Published in AIDS Weekly, May 29th, 2000

Researchers have received approval for a new clinical trial to test carefully controlled interruptions in HIV patients' drug regimens as an approach to boosting their immune systems, eventually to the point where they can manage their infections without the need for drugs.

Patient recruitment will begin immediately for the trial, which was conceived by a team of scientists headed by Luis J. Montaner, DVM, DPhil, an assistant professor at The Wistar Institute, and will be overseen by clinicians in the University of Pennsylvania Health System.

Current state-of-the-art therapy for HIV infection is to administer a cocktail of three drugs that...

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