AIDS Therapies

Kidney Disease Attributed to Reaction to Antiviral

Published in AIDS Weekly, June 12th, 2000

Medical investigators at Indiana University's School of Medicine report that patients taking the drug indinavir, an antiretroviral agent used in treating patients with the human immunodeficiency virus (HIV), has caused asymptomatic crystalluria and acute interstitial nephritis in at least two of their patients.

In describing some of the symptomatology associated with these kidney disorders, M. Jaradat and colleagues said, "Patients taking indinavir may present with asymptomatic crystalluria, nephroliathiasis with frank renal colic and obstruction, flank pain in the absence of nephrolithiasis, and dysuria or urgency."

These two patients were...

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Source: AIDS Weekly (2000-06-12)

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