Vertical Transmission

Interferon in Placenta Doesn't Prevent HIV in Infants

Published in AIDS Weekly, June 26th, 2000

Although interferons are expressed in the placenta of infants before birth, these cytokines with antiviral properties cannot effectively overcome the transmission of human immunodeficiency virus (HIV) from the mother to the infant.

V. Zachar and associates in the Department of Virus and Cancer at the Danish Cancer Society studied vertical transmission of HIV in a group of African women ("Lack of protection against vertical transmission of HIV-1 by interferons produced during pregnancy in a cohort from East African Republic of Malawi," Journal of Medical Virology, June 2000;61(2):195-200).

In this study, 43 women with HIV type 1 (HIV-1), 48...

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Source: AIDS Weekly (2000-06-26)

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