HIV Vaccines
Recombinant Yeast Delivers Antigen to Dendritic Cells
Published in AIDS Weekly, July 3rd, 2000
"Vaccine strategies that primarily elicit cellular immune responses are likely to be most effective in controlling progression of, or in protecting against HIV infection," said Andy C. Stubbs and colleagues from the University of Colorado and Ceres Pharmaceuticals Ltd., Colorado. "We previously have shown that immunization of mice with yeast expressing HIV-1 gp160 resulted in a strong anti-HIV cytotoxic T-lymphocyte (CTL) response.
"DC are the most potent antigen presenting cell (APC) known to initiate Ag-specific major...
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Source: AIDS Weekly (2000-07-03)
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