Published in AIDS Weekly, August 14th, 2000
"Envelope glycoprotein gp120 is located on the outer surface of HIV-1 and is exposed as a target for antibodies during HIV-1 infection," reported Diana I. Bejan and colleagues from Albany Medical College, New York, and the U.S. Department of Defense, Maryland. "In order to stimulate protective antiviral mucosal immunity to HIV-1, we have used the Th1-inducing cytokine, IL-12, alone or in combination with the mucosal adjuvant CTB for intranasal (i.n.) immunization with the gp120 glycoprotein...
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