AIDS Therapies
Nucleoside Analogue Reverse Transcriptase Inhibitors Contribute to Fat Wasting
Published in AIDS Weekly, September 4th, 2000
"Progressive subcutaneous fat wasting, fat accumulation, dyslipidemia, and insulin resistance in HIV infected patients on antiretroviral therapy have been attributed to the long-term toxicity of HIV protease inhibitors (PI)," stated S.A. Mallal and colleagues, Royal Perth Hospital, Australia. "More recently, fat wasting has been observed in patients who have never taken a PI, implicating an independent effect of nucleoside analogue reverse transcriptase inhibitor (NRTI) therapy."
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Source: AIDS Weekly (2000-09-04)
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