HIV Lipodystrophy Syndrome

Metformin Used as Treatment

Published in AIDS Weekly, September 4th, 2000

Metformin may be of benefit to HIV patients with lipodystrophy syndrome, suggest the results of a clinical trial.

"Context A syndrome of lipodystrophy, characterized by fat redistribution and insulin resistance, has been estimated to affect the majority of HIV infected individuals who are treated with combination antiretroviral therapy," stated C. Hadigan and colleagues, Massachusetts General Hospital, Massachusetts. "There are no proven therapies for the metabolic disturbances associated with HIV lipodystrophy syndrome."

The researchers conducted a randomized, double-blind, placebo-controlled pilot study, therefore, assessing safety and efficacy of...

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Source: AIDS Weekly (2000-09-04)

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