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HIV Gene Therapy

Engineered Red Blood Cells Act as Decoys for HIV

Published in AIDS Weekly, October 30th, 2000

Genetically engineering red blood cells to express the CD4 receptor may be a way to "fool" HIV in vivo, researchers in Australia suggest.

"Early stages of HIV infection are associated with an acute phase of viremia followed by a chronic, clinically latent period that may last as long as 10 years," stated R.F. Minchin and A.S. Cronin, University of Western Australia. "Decreasing total body viral burden during these early phases of infection may not only prolong the chronic latent period but also decrease the likelihood for viral transmission."

Minchin and Cronin presented data from their study at the conference Gene, Drug Therapy, and Molecular...

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