Viral Genetics
Novel Assay Quantifies HIV-1 Group M and Group O Subtypes
Published in AIDS Weekly, November 20th, 2000
"Human immunodeficiency virus type 1 (HIV-1) genetic diversity presents a challenge to nucleic acid-based assays with regard to sensitivity of detection and accuracy of quantification," stated P. Swanson and colleagues, Abbott Labs, Illinois. "The Abbott LCx HIV RNA Quantitative assay (LCx(R) HIV assay), a competitive RT-PCR [reverse transcriptase-polymerase chain reaction] targeting the pol integrase region, was evaluated using a panel of 297 HIV-1 seropositive plasma samples from Cameroon, Uganda, Brazil, Thailand, Spain,...
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Source: AIDS Weekly (2000-11-20)
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