Drug Resistance

Phenotypic Testing Can Predict HIV Treatment Failure at Low Viral Loads

Published in AIDS Weekly, January 8th, 2001

A study published in the December 22, 2000, issue of AIDS demonstrated for the first time that phenotypic HIV drug resistance testing can detect the emergence of drug resistance prior to a significant increase in viral load in patients undergoing antiretroviral therapy.

The study may have important clinical implications, as the successful use of drug resistance testing at low viral loads may help physicians change a failing treatment regimen earlier, before HIV develops high levels of resistance.

"To date, drug resistance tests have only been used after a patient's treatment fails," said study co-author Dr. Steven G. Deeks of the University of...

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Source: AIDS Weekly (2001-01-08)

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