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AIDS Therapies

Phase I SBIR Grant Awarded to Develop HIV Treatments

Published in AIDS Weekly, January 8th, 2001

PTC Therapeutics, Plainfield, New Jersey, announced that it has been awarded a Phase I Small Business Innovation Research (SBIR) grant from the U.S. National Institutes of Health (NIH).

Funding from this grant will be used to advance PTC's RNA-based approach for developing novel HIV drugs that target the mechanism the virus uses to replicate. The company's unique approach is based on interfering with an essential protein production process - called "programmed ribosomal frameshifting" - required by the virus for its survival.

The usual process of producing proteins is highly accurate and ensures that individual mRNAs will almost always lead to very...

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