AIDS Therapies

Older HIV Patients Less Likely to Realize Long-Term Benefit

Published in AIDS Weekly, February 5th, 2001

- by Michael Greer, staff medical writer -- The age of HIV patients treated with antiretroviral drugs and protease inhibitors apparently impacts the extent of immune system restitution they can derive from that therapy.

M.M. Lederman and colleagues at the University Hospital in Cleveland, Ohio, performed a study to "to characterize early and later indices of cellular restoration among HIV-1 infected persons treated with abacavir and one protease inhibitor and...identify predictors of CD4 cell increases."

They recruited 71 patients naive to antiretroviral therapy for a 48-week study, using flow-cytometric analyses to measure lymphocyte levels in these...

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Source: AIDS Weekly (2001-02-05)

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