Pathogenesis
CD8 Cells Can Prevent CD4+ Cell-Harbored Virus Replication
Published in AIDS Weekly, March 12th, 2001
The researchers found that autologous CD8+ cells were capable, in long-term nonprogressors (LTNPs) and patients responsive to highly active antiretroviral therapy (HAART), of preventing CD4+ cell-harbored virus replication ex vivo.
"CD8+ T-cell-mediated antiviral activity against HIV has been described consistently in infected individuals," explained T.W. Chun and colleagues with the U.S. National Institute of Allergy and Infectious Diseases.
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Source: AIDS Weekly (2001-03-12)
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