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HIV Vaccines

Simian Virus Mimics HIV Disease Course

Published in AIDS Weekly, March 26th, 2001

by N.R. Saltmarsh, staff medical writer - Assessing the usefulness of new HIV vaccines depends in large part on the animals in which they are tested. The more closely their disease mimics human HIV, the more accurate the results.

Now researchers at the Aaron Diamond AIDS Research Center in New York have isolated a simian HIV virus that appears to follow the same course as human immunodeficiency virus culminating in AIDS.

"Nonhuman primate models are increasingly used in the screening of candidate AIDS vaccine and immunization strategies for advancement to large-scale human trials," reported J.M. Harouse and colleagues. "The predictive value of such...

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