Adverse Drug Effects

Dopaminergic Drugs Can Hasten Neurologic Damage In HIV Patients

Published in AIDS Weekly, March 26th, 2001

by Michael Greer, staff medical writer - Dopaminergic drugs can aggravate brain and central nervous system (CNS) damage resulting from HIV infection, researchers in Germany report.

S. Czub and colleagues at the University of Wurzburg explained that HIV "at late stages of the disease is accompanied by neurological complications, including motor, behavioral, and cognitive impairment."

After finding dopamine deficits in the brains of monkeys infected with the simian version of HIV (SIV), Czub et al. studied the benefits of drugs that replenish dopamine supplies. However, they made the alarming discovery that such drugs only make matters worse.

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Source: AIDS Weekly (2001-03-26)

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