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HIV Vaccines

Clinical Trials Appropriate For High-Risk Cohorts In U.S.

Published in AIDS Weekly, April 23rd, 2001

by N.R. Saltmarsh, staff medical writer - A prospective study of human immunodeficiency virus type 1 (HIV-1) incidence among high-risk cohorts lends support to the idea that HIV-1 vaccine trials would be appropriate and welcomed in these populations in the United States.

"Questions exist about whether testing of preventive HIV-1 vaccines, which will require rapid recruitment and retention of cohorts with high HIV-1 seroincidence, is feasible in the United States," said G.R. Seage, III, and colleagues in the HIVNET Vaccine Preparedness Study group at the Harvard School of Public Health.

They conducted a prospective cohort study in 1995-1997 among...

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