Published in AIDS Weekly, May 21st, 2001
"Only a small fraction of [Env glycoprotein] gp160 appears to be ... transported to the cell surface, which makes it difficult to identify negative sequence elements regulating steady-state surface expression of Env at the post-ER [endoplasmic reticulum] level," Jurgen Haas and colleagues explained in the Journal of Virology.
Haas and colleagues devised a method to isolate Env-regulating motifs, which yielded two sequences shown to inhibit surface Env expression, they...
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