Vaccine Development

Tat Protein, Component Of HIV Vaccines, Has Been Successfully Produced In Spinach

Published in AIDS Weekly, June 4th, 2001

The success of combating AIDS in the most affected and least developed parts of the world will ultimately depend upon logistics and economics of vaccine production and delivery in a harsh and very poor environment. Plants represent an inexpensive and safe production and delivery vehicle, especially edible plants like spinach.

The key regulator of the HIV-1 replication, a small protein named tat, has been successfully produced in an edible plant - spinach. This is a first step to the production of a combination vaccine against HIV-1 entirely in plants.

The work was done by Dr. Alexander Karasev and Prof. Hilary Koprowski from the Biotechnology...

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Source: AIDS Weekly (2001-06-04)

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