AIDS Therapies

T-Cell Receptor Excision Circles Help Evaluate Pediatric Response

Published in AIDS Weekly, June 18th, 2001

by Michael Greer, senior medical writer - Measuring levels of T-cell receptor gene rearrangement excision circles (TRECs) in pediatric HIV patients can be helpful in determining their response to immune-restoring treatment, researchers in New York say.

"Immune reconstitution after antiretroviral therapy in [HIV] infected patients may result from the recovery of thymus function, peripheral redistribution, or decreased T-cell destruction," explained S. Chavan and colleagues at the North Shore Long Island Jewish Research Institute in New York.

Determining TREC levels in young patients can help pinpoint the source and degree of immune recovery following...

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Source: AIDS Weekly (2001-06-18)

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