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Immunology

Drug-Resistant HIV Allows Body To Continue Producing Virus-Fighting Cells

Published in AIDS Weekly, June 18th, 2001

HIV that has become resistant to powerful drugs called protease inhibitors may not be a dire sign of decline after all, researchers from the Gladstone Institute of Virology and Immunology at the University of California, San Francisco, have shown.

Published in the June 2001 issue of Nature Medicine, the study shows that drug-resistant HIV is less able to infect the thymus, the organ that churns out virus-fighting T cells. These patients can then continue to produce new T cells even in the face of high viral loads.

"It's potentially good news for patients who are on drugs and tolerating them," said lead author Cheryl Stoddart, PhD, staff...

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