Published in AIDS Weekly, June 18th, 2001
"The adenine nucleotide bias together with the poor fidelity of HIV 1 reverse transcriptase markedly enhances the genetic variation of HIV and may be responsible for the rapid emergence of drug-resistant HIV 1 strains," explained Jan Balzarini and colleagues at Katholieke Universiteit Leuven.
Balzarini and colleagues showed that it was possible to change the nucleotide bias of HIV, which may slow or halt the...
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