Screening
HIV Drug-Resistance Test Can Detect Resistance To Lopinavir
Published in AIDS Weekly, July 23rd, 2001
The addition means that the VirtualPhenotype reports a quantitative prediction of the level of phenotypic resistance of an HIV strain to all 15 of the HIV drugs currently available. The report uses unique biological cut offs, based on the natural variation of HIV, to classify a patient's test results as either "within" or "above" the "normal susceptible range" for each drug. For lopinavir this cut off is set at 2.5 (indicating a 2.5-fold change in resistance relative to the wild-type laboratory control strain), which is...
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Source: AIDS Weekly (2001-07-23)
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