Non-Hodgkin Lymphoma

Dysfunctional Cytotoxic T Cells Underlie Pathogenesis

Published in AIDS Weekly, September 3rd, 2001

by Michael Greer, senior medical writer - Researchers in Europe have shown that functional deficits in some immune cells may be a factor in the development of AIDS-related lymphomas.

"Acquired immunodeficiency syndrome-related non-Hodgkin lymphomas (AIDS-NHL) are thought to arise because of loss of Epstein-Barr Virus (EBV)-specific cellular immunity," according to Debbie van Baarle and colleagues at the Central Laboratory of the Netherlands Red Cross Blood Transfusion Service, the University of Amsterdam, Rotterdam University Hospital and the United Kingdom's Institute of Molecular Medicine.

Compromised EBV-specific immune function is a result of...

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Source: AIDS Weekly (2001-09-03)

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