HIV Therapies

FDA Approves Tenofovir Disoproxil Fumarate For Treatment Of HIV Infection

Published in AIDS Weekly, November 12th, 2001

The U.S. Food and Drug Administration (FDA) has approved Viread (tenofovir disoproxil fumarate), a new antiviral drug indicated for treatment of HIV-1 infection in combination with other antiretroviral medicines.

Tenofovir disoproxil fumarate is the first nucleotide analog approved for HIV-1 treatment. Nucleotides are similar to nucleoside analogs, and block HIV replication in the same manner.

The introduction of potent antiviral drugs and the combined use of these drugs has markedly reduced replication of HIV in many patients and has improved survival rates. Yet because HIV mutates rapidly, resistance to one or more of these potent drugs may...

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Source: AIDS Weekly (2001-11-12)

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