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AIDS And HIV Vaccine
New Details About Epitope Targeted By Potent Monoclonal Antibody
November 19th, 2001
by Michael Greer, senior medical writer - Researchers in the United States and Europe say that they have shed new light on a potential HIV vaccine target. In a multi-institutional study, Carol E. Parker, University of North Carolina - Chapel Hill, and colleagues sought to "identify the functional epitope on human immunodeficiency virus envelope glycoprotein gp41 for the broadly neutralizing anti-gp41 human monoclonal antibody 2F5." With the aid of mass spectrometry, Parker and coworkers were able to provide new details about the structure of this important epitope. The researchers first bound a soluble form of gp140 protein to...
Source: AIDS Weekly (2001-11-19)
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