AIDS and HIV Pathogenesis

Memory T-Cell Populations Affect Viral Load

Published in AIDS Weekly, December 24th, 2001

by Michael Greer, senior medical writer - The makeup of antigen-specific memory T-cell populations influences viral load in the acute phase of HIV infection, according to researchers in the United States.

Dr. Elizabeth Connick and colleagues at the University of Colorado Health Sciences Center in Denver and the Denver Department of Public Health examined the effect of precursor cytotoxic T lymphocytes (CTLs) on HIV RNA levels.

Memory T cells targeting certain antigens were associated with higher viral loads than cells specific to other antigens, they found.

Each of the 14 recently infected study participants demonstrated memory...

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Source: AIDS Weekly (2001-12-24)

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