AIDS and HIV Therapy
Novel oligonucleotide shows promise as treatment
Published in AIDS Weekly, March 11th, 2002
Jun-ichiro Suzuki and colleagues at the Chiba Institute of Technology in Chiba and Tohoku University in Sendai evaluated the antiviral efficacy of a phosphorothioate-containing oligonucleotide with a basket-type dimeric hairpin guanosine quadruplex, according to their report in the March 2002 edition of the Journal of Virology.
This piece of genetic material was able to block HIV cell entry and replication, Suzuki and coauthors reported.
The oligonucleotide studied,...
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Source: AIDS Weekly (2002-03-11)
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