Published in AIDS Weekly, April 29th, 2002
"Nef enhances human immunodeficiency virus type 1 (HIV-1) infectivity in culture and stimulates viral replication in primary T cells," explained Christopher A. Lundquist and colleagues at the Vanderbilt University School of Medicine in Nashville, Tennessee.
Lundquist and coauthors found a strong link between Nef-induced CD4 downregulation and enhanced viral proliferation.
The researchers compared the virulence of designer HIV strains...
Want to see the full article?
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of AIDS Weekly
NewsRx also is available at LexisNexis, Gale, ProQuest, Factiva, Dialog, Thomson Reuters, NewsEdge, and Dow Jones.