Immunology

Drug breaks for HIV-infected individuals may put certain immune cells at risk

Published in AIDS Weekly, May 27th, 2002

Disruption of antiretroviral therapy by patients infected with HIV may be putting certain T cells in their bloodstream at greater risk for infection with the deadly virus if it is allowed to rebound, a study in the May 2, 2002, issue of the journal Nature concludes.

Patients whose viral counts have fallen to nearly imperceptible levels sometimes interrupt antiviral therapy temporarily, restarting treatment if viral levels rebound. Called structured therapy interruption, these drug breaks can increase the number of certain HIV-fighting T cells, called CD8 T-cells, in the blood. Another type of T cell, CD4, also plays an important role in fighting HIV.

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Source: AIDS Weekly (2002-05-27)

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