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AIDS Therapy

Roche adds MV026048 to its HIV treatment portfolio

Published in AIDS Weekly, June 24th, 2002

Roche has signed a licensing agreement with Medivir, a Swedish biotechnology company, for MV026048, a treatment in development for HIV.

A novel nonnucleoside reverse transcriptase inhibitor (nNRTI), MV026048 is currently in preclinical development and is expected to enter phase I clinical studies in 2003.

Current nNRTIs share common resistance profiles, which may reduce the likelihood that a patient will benefit from a second currently approved nNRTI after failing therapy with a first nNRTI. Preclinical data for MV026048 indicate that this new generation compound has a unique resistance profile. A unique resistance profile could make MV026048 a...

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