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AIDS Therapy

Researchers develop HIV fighter

Published in AIDS Weekly, July 8th, 2002

A form of RNA developed by researchers at the Massachusetts Institute of Technology silences genes that play a role in HIV infection, potentially showing a new way to combat the virus that causes AIDS.

The team used short forms of RNA - ribonucleic acid - that turn off genes vital for the production of proteins used by the virus to enter and infect cells. RNA carries the blueprint for constructing proteins.

"If many obstacles can be surmounted this could be a basis for intervention in HIV treatment," said Dr. Phillip A. Sharp, who led the research.

The work was conducted in the laboratory, and problems to be solved include...

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