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AIDS and HIV Vaccine

Antibody-resistant infection poorly controlled after DNA prime/boost regimens

Published in AIDS Weekly, July 15th, 2002

by Michael Greer, senior medical writer - Potential HIV vaccines effective against some simian strains may not provide similar protection from the human version, researchers warn.

"In the rhesus macaque model, some protection was afforded by DNA/recombinant viral vector vaccines," according to Helen Horton, Wisconsin Regional Primate Research Center, and a multicenter team in the U.S. and Europe and at PowderJect Vaccines, Inc., in Madison, Wisconsin.

However, many HIV strains may not be as vulnerable as the simian strain used in many primate studies, Horton and coauthors found.

Researchers studying candidate vaccines often...

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