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HIV/AIDS Therapy

Novel technique enables single-cell latency analysis

Published in AIDS Weekly, September 2nd, 2002

by Michael Greer, senior medical writer - Researchers in the United States have developed a novel technique for studying latent HIV infection.

"The ability of human immunodeficiency virus type 1 (HIV-1) to establish latent infections in cells has received renewed attention owing to the failure of highly active antiretroviral therapy to eradicate HIV-1 in vivo," according to Olaf Kutsch and colleagues at the University of Alabama at Birmingham and the Howard Hughes Medical Institute in Birmingham, Alabama. "Despite much study, the molecular bases of HIV-1 latency and reactivation are incompletely understood."

Kutsch and coauthors constructed a HIV...

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