Published in AIDS Weekly, September 30th, 2002
"Caveolin-1 (Cav-1) is a major protein constituent of caveolae, a type of plasma membrane raft," explained Manuel Llano and colleagues working at the Mayo Clinic in Rochester, Minnesota.
Cav-1 was able to selectively suppress the expression of key HIV proteins, Llano and coauthors found.
At low levels, Cav-1 prevented expression of HIV-1 and HIV-2 proteins, the researchers reported. Exposure to Cav-1 did not impair protein expression by other viruses and had no deleterious...
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