Pediatric HIV/AIDS
Resistance mutations common in children failing therapy
Published in AIDS Weekly, October 14th, 2002
"High levels of HIV-1 replication occur following perinatal infection and antiretroviral drugs may not fully suppress viral load during the early years of childhood," according to Jane Mullen and colleagues at King's College, Guy's and St. Thomas' Hospitals Trust, and St. George's Hospital in London. "Adherence to treatment may also be difficult among children."
These factors lead to a high rate of resistance mutations in children with HIV, especially among patients...
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Source: AIDS Weekly (2002-10-14)
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