Published in AIDS Weekly, November 4th, 2002
George Makedonas and colleagues at McGill University in Montreal and the University of Montreal assessed the impact of HIV-specific cytotoxic T lymphocyte activity on HIV-exposed, uninfected (EU) patients' risk of seroconversion.
Virus-specific CD8+ effector cell responses were associated with a significantly reduced seroconversion risk for drug users sharing needles with infected partners, Makedonas and coauthors found.
The researchers examined cytotoxic...
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