HIV/AIDS Pathogenesis

T cell receptor expression may affect progression rate

Published in AIDS Weekly, December 2nd, 2002

by Michael Greer, senior medical writer - A small group of T cell receptor proteins may play a key role in the rate of HIV progression, researchers in the United Kingdom report.

"It is still unclear why some patients with HIV progress more slowly than others to developing full blown AIDS," according to M.D. Bodman-Smith and colleagues working at the University of Leeds and the Camden and Islington Community Services National Health Service (NHS) Trust in Leeds.

Heightened expression of some T cell receptors by cytotoxic T cells was linked to slower disease progression, Bodman-Smith and coauthors found.

The researchers examined...

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Source: AIDS Weekly (2002-12-02)

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