Chancroid

Rapid immunodiagnostic test being developed for Haemophilus ducreyi

Published in AIDS Weekly, December 23rd, 2002

A monoclonal antibody-based immunodiagnostic test to the hemoglobin receptor of Haemophilus ducreyi is being developed by University of North Carolina, Chapel Hill, researchers.

"Haemophilus ducreyi is the etiologic agent of chancroid, a sexually transmitted disease that increases the rate of transmission of human immunodeficiency virus. Chancroid ulcerations are difficult to distinguish from those produced by syphilis and herpes. Diagnosis based solely on clinical grounds is inaccurate, and culture is insensitive," stated K. Patterson and colleagues. "Highly sensitive PCR has largely superseded culture as the preferred method of laboratory diagnosis;...

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Source: AIDS Weekly (2002-12-23)

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